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The human MAPEG superfamily includes six members: 5lipoxygenase activating protein (FLAP), leukotriene C 4 synthase (both involved in leukotriene synthesis), MGST1, MGST2, MGST3 (GSTs as well as glutathione dependent peroxidases) and prostaglandin E synthase (PGES) (Bresell et al., 2005)

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